Found 16 matching trials
GSK1120212+GSK2141795 for Cervical Cancer PHASE2 This research study is evaluating the combination of two drugs called GSK11...
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Dana-Farber Cancer Institute
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A Study of the Safety and Efficacy of Pembrolizumab (MK-3475) in Combination With Trametinib and Dabrafenib in Participants With Advanced Melanoma (MK-3475-022/KEYNOTE-022) PHASE1 This is a 5-part dose-finding and preliminary efficacy study of pembrolizum...
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Multiple Locations
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Study of Efficacy and Safety of Dabrafenib in Combination With Trametinib in Pediatric Patients With BRAF V600 Mutation Positive LGG or Relapsed or Refractory HGG Tumors PHASE2 The purpose of this study was to investigate the activity of dabrafenib in ...
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Children's Hospital of Orange County
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Trametinib + HDM201 in CRC Patients With RAS/RAF Mutant and TP53 Wild-type Advanced/Metastatic Colorectal Cancer Mutant and TP53 Wild-type PHASE1 Recent preclinical studies suggest that combining MEK and MDM2 inhibition s...
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Centre Leon Berard
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BRAF/MEK/EGFR Inhibitor Combination Study in Colorectal Cancer (CRC) PHASE1 This was a four part, phase I/II study aimed to evaluate the safety, tolera...
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Novartis Investigative Site
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Trametinib, Fluorouracil, and Radiation Therapy Before Surgery in Treating Patients With Stage II-III Rectal Cancer PHASE1 This phase I trial studies the side effects and best dose of trametinib whe...
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Siteman Cancer Center at Washington University
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Defining the Triple Negative Breast Cancer Kinome Response to GSK1120212 EARLY_PHASE1 Research into treatments for breast cancer relies more and more on an under...
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Lineberger Comprehensive Cancer Center
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Combination of Alpelisib and Trametinib in Progressive Refractory Meningiomas PHASE1 Aggressive growing meningiomas resistant to multiple surgeries and radiothe...
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Assistance Publique Hôpitaux de Marseille
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Capmatinib Plus Trametinib for the Treatment of Metastatic Non-small Cell Lung Cancer With MET Exon 14 Skipping Mutation PHASE1 This phase I/Ib trial studies the side effects and best doses of capmatinib...
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University of California San Francisco
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Trial of Trametinib and Ponatinib in Patients With KRAS Mutant Advanced Non-Small Cell Lung Cancer PHASE1 The purpose of this study is to evaluate the safety of the combination of p...
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Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities)
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